A man without choice who tries to take control of his own life; a policeman who is alarmed that his wife who was missing-at-sea has returned a different person; and a woman determined to find a specific someone with a special ability.
MANIAC tells the stories of Annie Landsberg (Emma Stone) and Owen Milgrim (Jonah Hill), two strangers drawn to the late stages of a mysterious pharmaceutical trial. Things do not go as planned.
