i'd like to answer JerZa (Jellal & Erza from Fairy Tail) but the story isn't over yet! :D
soooo uuhhhhhmmm... the animes i've watched barely has any couples at all :)) but Narunosuke & Haineko (which has already been posted) was tragic. technically they weren't a couple. but they would've been...
Every couple that exists in Puella Magi Madoka Magica i mean seriously Especially Homui/Mado and Kyo/Saya help im already tears kyOKO AND SAYAKA EVRN GOT HTHEIR OWN CHARATER SONG AND HERLP ITTS MAKIGN ME CRY
Okay: 이누야사 X Kikyo Ok kikyo is being mean (i know i don't like her in the past) But its the time 이누야사 said Goodbye to Kikyo... I know i hated her but this scene give me the chills. (sad face) But at the end 이누야사 ends up with Kagome. But still Inuyasha's first Girlfriend was Kikyo. and the part of kikyo's death is so SAD! :( :'( SO SAD!
Airi YūnamiXGutoku Asanagi from Qualidea Code. Airi was an extradimensional alien posing as a human, while Gutoku was a (mutated)human. Airi died to prevent her species(the Unknown) from doing further harm to our planet and mankind. At least it's implied Aoi Yaegaki is their child.